This is my favorite verse. I'll never convince the Bible publishers, but to me Genesis 3:10 is where the greatest Bible division occours. From this point until the worship gathering of Revelation 7, there is one story being played out, all foreshadowed by God's words in this early moment.
God's first recorded words to humankind reveal intent, “Be fruitful and multiply, and fill the waters in the seas, and let birds multiply on the earth." In the next recorded command God gave humankind valuable work and then clearly defined their relationship with God by explaining death would result if they disobeyed the parameters He set. It was a beautiful example of love from a Creator desiring to protect his creation.
Of course humankind was tempted and willfully rebelled against God by breaking those parameters. Death in the sense of separation from God was promised by God and indeed came upon all creation. Humankind knew they were dead and hid from God. More than hiding, they actually tried to cover themselves. In their silliness and new death nature humankind hears what I consider to be my favorite words, "Where are you."
They are my favorite because they are what I consider the defining characteristic of God's relationship with us. While we are yet sinners and going against His perfect plan for us He comes searching out that which is lost. He desires to bring life into humankind's situation of death. That is a lot of Christian language saying though we may have done horrible things, God is a searching God and desires to bring us back to life and relationship with Him. Love, grace, and mission all in one.
I could go on and on about how this begins God's mission that results in Jesus coming to seek and save that which is lost (Luke 19:10), but I just hope to reflect on this little moment in history that shows us a defining character of God. I just rejoice to know our God still seeks out sinful humankind in an effort to restore them back to life.